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Description
As the most abundant protein in human plasma, HSA is composed of 585 amino acids. It has a molecular weight of 66.5KD and an isoelectric point of 4.8. rHSA is widely used in biochemical experiments, such as being used as a blocking ragent in western, also plays a role in mailly maintaining the osmotic pressure, PH buffer and as carriers and nutritions. rHSA can also be used as a hapten carrier, a protective reagent, and in protein complementation control in cell culture.
Healthgen uses State-of-the-art platform called OryzHiExp, having high capacity to express proteins and peptides in the rice grain. The platform uses rice endosperm cells as a bioreactor to specifically and highly express various recombinant proteins and small peptides. The platform is a rice-specific endosperm cell-specific expression platform that focuses on the expression of animal-free products, safe recombinant proteins and peptides. We use this technique to express recombinant human serum albumin to achieve higher safety and biosafety. Healthgen recombinant human serum albumin (rHSA) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the rHSA, with the world's advanced facility and top production proceeding to extract and purify the rHSA, Healthgen can ensure the excellent consistency of rHSA from different batches.
Catalog No. | HY100M1 |
Physical Appearance | Off-white to light beige lyophilized powder |
Formulation | Lyophilized with saline |
Purity | More than 99% as determined by SDS-PAGE and HPLC analysis |
Endotoxin | Less than 0.25EU/mg |
Storage Condition | Stored at temperatures 2~8 ℃ for 24 months |
Healthgen Biotech has committed to albumin research for 10 years and has successfully developed and manufactured high-quality rHSA. We have excellent albumin sources, which are derived from rice endosperm cells; Our scale production facility is compliant with GMP. We have highly-sophisticated protein purification technology. Our quality control system has been certified by ISO 9001:2008 and ensure standardized process as well as qualified products. We can provide large-scale, high-quality and high batches stability albumins.
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Crystal Structure | Identical | Identical |
Supplemental Description
Healthgen Biotech has strong technical force and advanced and complete protein expression and purification technology development and large-scale production facilities. Self-developed rice endosperm cell expression platform (OryzHiExp), which is domestic initiative and the international leader, has such advantages: high expression level, safety, scale-up easily, simple production process and environmental protection etc. After 10 years of unremitting efforts, Healthgen Biotech has established recombinant protein expression and purification technology platform to customize recombinant protein or peptide expression and purification process service for pharmaceuticals, health products, scientific research and industrial reagents. Using the OryzHiExp platform, Healthgen Biotech has achievements in developing and commercializing a series of medium ingredients, including recombinant human serum albumin (OsrHSA), recombinant alphar-1 antitrypsin (OsrAAT), recombinant human lactoferrin (OsrLF), recombinant human basic fibroblast growth factor (OsrbFGF), recombinant human insulin-like growth factor-1 (OsrIGF-1) and recombinant human transferring(OsrTF), which can provide a full set of solutions for animal component free cell culture medium.